Volume 37, Issue 199 (August 2025)

Recent Development of Immunotherapy for Treating Glioblastoma With a Focus on CAR-T Cells

Gabriela Soltys, Mariana Moctezuma, Pauline Pham, Yuqi Wang

DM 2025, 37(199), 1423-1433; https://doi.org/10.24976/Discov.Med.202537199.125

Modulation of the Intestinal Barrier by Oral Bacteria in Inflammatory Bowel Disease

Xi Li, Kexin Chen, Yongbin Jia, Xingqun Cheng, Hongyin Lin, Zhipeng Li

DM 2025, 37(199), 1434-1448; https://doi.org/10.24976/Discov.Med.202537199.126

Circadian Rhythm Disruption and Its Association With Type 2 Diabetes Mellitus

Ming Zhong, Wei Li, Mengting Fan, Weiping Tu

DM 2025, 37(199), 1449-1464; https://doi.org/10.24976/Discov.Med.202537199.127

The Possible Therapeutic Effect of Huperzine A on the Cerebellar Cortex of a Rat Model of Autism: Behavioural and Histopathological Study

Saad Misfer Alqahtani, Khlood Mohammed Mehdar

DM 2025, 37(199), 1465-1478; https://doi.org/10.24976/Discov.Med.202537199.128

Piezo1 Activates the PI3K/Akt Pathway to Stimulate Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells and Speed Up Fracture Healing

Shengkai Mu, Xuanlu Qi, Haixia Hong, Honglai Tian

DM 2025, 37(199), 1479-1492; https://doi.org/10.24976/Discov.Med.202537199.129

Identification of Immune Evasion-Associated Genes in the Tumor Microenvironment of Hepatocellular Carcinoma and Development of a Prognostic Risk Model

ZhaoWen Bi, DeXue Fan, XinXing Wang, XiZhen Li, ZhenHai Zhang

DM 2025, 37(199), 1493-1509; https://doi.org/10.24976/Discov.Med.202537199.130

Micheliolide Induces Ferroptosis to Restrain the Malignant Phenotype of Non-Small Cell Lung Cancer Cells

Hong Lv, Tiefeng Qiu, Qinyu Xu

DM 2025, 37(199), 1510-1519; https://doi.org/10.24976/Discov.Med.202537199.131

Enhancing Antibacterial Properties of Flowable Dental Composites With Chlorhexidine: A Balance Between Efficacy and Bonding Strength – An In Vitro Study

Alison Prosper, Matthieu Minty, Amel Mansouri, Charlotte Marfaing, Djillali Yahiaoui, Pascale Loubieres, Vincent Blasco-Baque, Thibault Canceill

DM 2025, 37(199), 1520-1533; https://doi.org/10.24976/Discov.Med.202537199.132

Unveiling Key cGAS–STING Pathway-Related Molecular Players in Arteriosclerosis Development: A Comprehensive Bioinformatics Analysis

Fuzhen Zheng, Licheng Yan, Yuanxiang Chen, Deng Xie, Feng Zhu, Guoxing Weng

DM 2025, 37(199), 1534-1547; https://doi.org/10.24976/Discov.Med.202537199.133

Translating Proteomic Profiles Into Therapeutic Targets: A Mendelian Randomization Analysis in Breast Cancer

Qian Min, Yi Dong, Qingqing Li, Yi Yao

DM 2025, 37(199), 1548-1558; https://doi.org/10.24976/Discov.Med.202537199.134

Identification and Analysis of Gut Microbiota in Different Severity of Sepsis Patients and CLP-induced Rats

Haiyong Zhu, Kailun Hu, Jiansong Yu, Dan Li

DM 2025, 37(199), 1559-1571; https://doi.org/10.24976/Discov.Med.202537199.135

In Silico Analysis Reveals Overlapping Molecular Mechanisms Between COVID-19 and Attention-Deficit/Hyperactivity Disorder

Ma. Mikaella Rosales, Sohi Kang, Mary Jasmin Ang, Changjong Moon

DM 2025, 37(199), 1572-1585; https://doi.org/10.24976/Discov.Med.202537199.136

Efficacy and Safety of Neoadjuvant Chemoimmunotherapy in Patients With Muscle-Invasive Bladder Cancer

Quanqi Liu, Pengfei Zhou, Daxue Tian

DM 2025, 37(199), 1586-1594; https://doi.org/10.24976/Discov.Med.202537199.137

Role of TRIM37 in Cervical Cancer: Its Effects on Tumor Cells Proliferation, Migration, and Invasion

Ailin Sun, Qiuyang Zhang, Tiantian Zhao, Fei Gao, Tiefang Song

DM 2025, 37(199), 1595-1603; https://doi.org/10.24976/Discov.Med.202537199.138

Circ_0049271: A Novel Circular RNA Biomarker for Diagnosis and Prognostic Assessment in Acute Myocardial Infarction

Huocheng Liao, Chun Xiao, Weiwei Li, Wenzhong Chen, Dingcheng Xiang

DM 2025, 37(199), 1604-1612; https://doi.org/10.24976/Discov.Med.202537199.139

Clinical and Molecular Characteristics Associated With Pleural Metastasis in Advanced Non-Small Cell Lung Cancer

Lei Gong, Zhiyu Huang, Sizhe Yu, Kaiyan Chen, Junrong Yan, Mengyun Wang, Yun Fan, Ming Chen

DM 2025, 37(199), 1613-1621; https://doi.org/10.24976/Discov.Med.202537199.140

Dysfunctional Uterine Bleeding and the Stress Axis

Ümran Karabulut Doğan, Abdullah Karaer, Sedat Yıldız

DM 2025, 37(199), 1622-1629; https://doi.org/10.24976/Discov.Med.202537199.141

Pachymic Acid A Alleviates Myocardial Injury in Acute Myocardial Infarction Mice by Regulating the AMPK/mTOR Pathway-Mediated Autophagy

Zhaozheng Liu, Qu Jin, Jinzhu Yin

DM 2025, 37(199), 1630-1638; https://doi.org/10.24976/Discov.Med.202537199.142

Association Between Neutrophil-to-Lymphocyte Ratio and Lymphovascular Space Invasion in Endometrial Cancer: A Single-Center Cross-Sectional Study With Survival Analysis

Lixia Xu, Zhen Hu, Junqiang Du

DM 2025, 37(199), 1639-1650; https://doi.org/10.24976/Discov.Med.202537199.143

Bafilomycin A1 Potentially Enhances Mesenchymal Stem Cell-derived Extracellular Vesicle Production in iPSC-MSC Cultures

Yuping Xiao, Weiyi Yuan, Shihong Chen, Gensheng Zhang, Qingling Fu, Zhijian Cai, Xinliang Lu

DM 2025, 37(199), 1651-1662; https://doi.org/10.24976/Discov.Med.202537199.144

MDFI Promotes NSCLC Cell Proliferation and Migration by Modulating Autophagy

Guoliang Ma, Jing Lin, Miaolin Yu, Yuguo Ren

DM 2025, 37(199), 1663-1676; https://doi.org/10.24976/Discov.Med.202537199.145

GATA4-Overexpressing Dental Pulp Stem Cells Repair Infarcted Myocardium in Acute Myocardial Infarction Rats

Jinxin Lv, Yan Wang, Yanghong Dong, Yi Wu, Lu Fu

DM 2025, 37(199), 1677-1698; https://doi.org/10.24976/Discov.Med.202537199.146

Cryptococcus Osteomyelitis in Humans—A Systematic Review

Petros Ioannou, Afroditi Ziogou, Alexios Giannakodimos, Ilias Giannakodimos, Andreas G Tsantes, George Samonis

DM 2025, 37(199), 1699-1712; https://doi.org/10.24976/Discov.Med.202537199.147

Selecting the Right RORγt Agonist: Implications for Cancer Immunotherapy

Marcin Ratajewski

DM 2025, 37(199), 1713-1717; https://doi.org/10.24976/Discov.Med.202537199.148

Reprogramming Therapeutics: Synthetic Biological Constructs at the Frontier of Precision Medicine

Amol D. Gholap, Navnath Hatvate, Abdelwahab Omri

DM 2025, 37(199), 1718-1720; https://doi.org/10.24976/Discov.Med.202537199.149