With the accelerated pace of modern life and evolving work patterns, an increasing number of individuals experience circadian rhythm reversal and irregular work-rest schedules. This altered lifestyle profoundly impacts the human metabolic system, particularly by elevating the risk of type 2 diabetes. Alterations in circadian rhythms may heighten this risk of type 2 diabetes through mechanisms such as interference with insulin secretion and glucose metabolism. This study reviewed the circadian rhythm system, behaviors associated with circadian dysregulation and diabetes, circadian rhythm synchronization, and metabolic health to provide scientific evidence for managing type 2 diabetes induced by circadian rhythm disruption.