Volume 37, Issue 195 (April 2025)

Comparative Analysis of Anterior vs Posterior Approaches in Eyelid Ptosis Repair

Marco Zeppieri, Vito Cazzato, Pier Luigi Surico, Glenda Giorgia Caputo, Pier Camillo Parodi, Fabiana D’Esposito, Mutali Musa, Caterina Gagliano, Anna Scarabosio

DM 2025, 37(195), 598-607; https://doi.org/10.24976/Discov.Med.202537195.52

GPCRs With mTOR Signaling Expressed in Gut-Brain-Immune Axis-Cells Could Contribute to the Treatment of Neurodegenerative Diseases and Immune-Related Diseases

Akari Fukumoto, Naoko Suga, Moeka Nakashima, Satoru Matsuda

DM 2025, 37(195), 608-617; https://doi.org/10.24976/Discov.Med.202537195.53

CAR-T Therapy for the Treatment of Colorectal Cancer

Arturo Lecumberri, Hugo Arasanz, Irene Caseda, Ana Elsa Huerta, Natalia Castro, Ibone Labiano, Maria Alsina, Natalia Ramirez, Ruth Vera

DM 2025, 37(195), 618-630; https://doi.org/10.24976/Discov.Med.202537195.54

Immunomodulatory Role of T Cell Immunoglobulin and Mucin Domain-3 in Cancer

Avinash Chaudhary, Pragya Yadav, Pratima Chaudhary, Shweta Sargam, Partha Pratim Manna

DM 2025, 37(195), 631-646; https://doi.org/10.24976/Discov.Med.202537195.55

(This article belongs to the Special Issue Immunomodulators as Adjuvant Therapies in Cancer)

Interleukins in Urological Diseases

Hakan AKDERE, Burak BILIR, Hasan Can KUVAN, Gokhan CEVIK

DM 2025, 37(195), 647-658; https://doi.org/10.24976/Discov.Med.202537195.56

Protective Role of Protocatechuic Acid in Glioma: Modulation of Cell Growth, Migration, and Pyroptosis via NLRP3/Caspase-1/GSDMD Axis

Wen Zhang, Yeyan Cai, Haijun Zheng

DM 2025, 37(195), 659-668; https://doi.org/10.24976/Discov.Med.202537195.57

Celastrol Targets FANCD2 to Induce Autophagy-Dependent Ferroptosis in Hepatocellular Carcinoma Cells

Jici Yan, Tian Xu

DM 2025, 37(195), 669-684; https://doi.org/10.24976/Discov.Med.202537195.58

Sirtuin1 Promotes the Migration of Cells and Reduces the Accumulation of Extracellular Matrix in Trabecular Meshwork Cells Induced by Transform Growth Factor-β via Smads System

Jinjun Tie, Junhong Guo, Jiemei Yuan, Jiantao Wang

DM 2025, 37(195), 685-694; https://doi.org/10.24976/Discov.Med.202537195.59

Investigating the Mechanisms of Esketamine in Treating Propofol-Induced Cognitive Impairment in Elderly Rats

Jieru Zhang, Guofeng Xu, Xiaoli Wang, Leyan Qiao

DM 2025, 37(195), 695-705; https://doi.org/10.24976/Discov.Med.202537195.60

Effects of Botulinum Toxin A on Condylar Subchondral Bone Mass

Linqing Tian, Ye He, Wenli Zhang, Wenying Yang, Cong Jiang, Dongping He, Enyu Mao, Yingwei Luo, Xun Sheng

DM 2025, 37(195), 706-714; https://doi.org/10.24976/Discov.Med.202537195.61

Protective Role of Cerium Oxide Nanoparticle Pretreatment in Preventing Pilocarpine-Induced Epileptic Seizures

Dan Yang, Shuangfeng Yang, Jingya Deng, Xiyue Fan, Guohui Jiang, Fei Yang, Xiaoming Wang

DM 2025, 37(195), 715-726; https://doi.org/10.24976/Discov.Med.202537195.62

Exploring the lncRNA NEAT1/iASPP Pathway in Chordoma: Mechanisms of Proliferation Suppression and Apoptosis Induction

Zhigang Ma, Lei Wang, Zhe Ji, Hongwei Li

DM 2025, 37(195), 727-736; https://doi.org/10.24976/Discov.Med.202537195.63

A Potential Link Between Early Onset Reactive Astrogliosis and Adult-Onset Dysfunction of Leptin Signaling in Polyubiquitin Gene Ubb Knockout Mice

Jin-Sil Bae, Sekee Yoon, Taek-Yeong Kim, Kwon-Yul Ryu

DM 2025, 37(195), 737-749; https://doi.org/10.24976/Discov.Med.202537195.64

SPAG4 Regulates Glycolytic Metabolism in HT29 Cells as a Target via the c-MYC/SULT2B1 Pathway

Honghong He, Xuebing Zhang, Liting Zhong, Ting Li, Jinquan Ding, Shilai Wen

DM 2025, 37(195), 750-764; https://doi.org/10.24976/Discov.Med.202537195.65

Effects of Aerobic Exercise and Intermittent Fasting on Fecal Microbiome Diversity in Obese Mice

Lingfeng Yuan, Yisheng Luan, Weihao Hong, Bing Zhang, Yingzhe Xiong

DM 2025, 37(195), 765-771; https://doi.org/10.24976/Discov.Med.202537195.66

Curcumin Attenuates PD-L1-Positive Neutrophil-Induced T-Lymphocyte Apoptosis and Alleviates Lung Injury During Sepsis in Rats

Jiajun Zou, Jian Guo, Guanyu Hu, Yiming Qian

DM 2025, 37(195), 772-782; https://doi.org/10.24976/Discov.Med.202537195.67

The Relationship of MAPK10P Gene Polymorphism With P-Wave Peak Time and P-Wave Dispersion in Elderly Patients With Paroxysmal Atrial Fibrillation

WenYi Wang, Gang Liang, AiLin Bian, Di Luo, Lin Cai, XiaoFei Wang

DM 2025, 37(195), 783-790; https://doi.org/10.24976/Discov.Med.202537195.68