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Discovery Medicine

Print ISSN: 1539-6509Online ISSN: 1944-7930

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Immunomodulators as Adjuvant Therapies in Cancer

Submission Deadline: 1 Mar 2026

Special Issue Information

Dear Colleagues,

Despite the significant advances in cancer treatment attained in recent years, challenges such as drug resistance and adverse side effects continue to plague the therapeutic efforts. Nevertheless, the incorporation of immunomodulators stands out to be a promising strategy for enhancing the efficacy and safety of conventional cancer treatments. The objective of this special issue is to explore the potential of immunomodulators as adjuvant therapies to improve cancer outcomes.

This special issue welcomes submissions that examine the mechanisms influencing immunological pathways and enhancing anti-tumor immunity. Additionally, we invite contributions that examine the potential of immunomodulatory compounds that act synergistically with standard cancer therapies. Topics of interest include, but are not limited to, the identification of novel immunomodulators, their effects on immune cells and immune-related mechanisms (e.g., inflammatory markers), and translational studies evaluating their therapeutic potential. By convening leading experts in this field, this special issue is primed to advance our understanding of how to effectively enhance immune response by incorporating immunomodulators into standard cancer treatment regimens.

Dr. Yamixa Delgado
Guest Editor

Keywords

  • immunomodulators
  • cancer
  • immune response
  • adjuvant therapies
  • anti-tumor immunity
  • immunotherapeutics

Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at https://www.discovmed.com/Journalx_dm/authorLogOn.action by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.

Published Papers (4)

Review
Review
Immunomodulatory Role of T Cell Immunoglobulin and Mucin Domain-3 in Cancer

Avinash Chaudhary, Pragya Yadav, Pratima Chaudhary, Shweta Sargam, Partha Pratim Manna

DM 2025, 37(195)631-646; https://doi.org/10.24976/Discov.Med.202537195.55

(This article belongs to the Special Issue Immunomodulators as Adjuvant Therapies in Cancer)

Review
Unlocking the Potential of Immunomodulators as Synergistic Immune-Based Therapies in Cancer

Shivani Tomar, Saleha Siddiqui, Rajiv Pathak, Vivek Srivastava

DM 2025, 37(194)411-432; https://doi.org/10.24976/Discov.Med.202537194.35

(This article belongs to the Special Issue Immunomodulators as Adjuvant Therapies in Cancer)

Review
Uncommon but Significant: Onset, Characteristics and Management of Vasculitis and Connective Tissue Diseases Induced by Immunomodulators during Cancer Treatment

Caterina Gagliano, Roberta Foti, Elisa Visalli, Edoardo Dammino, Antonino Maniaci, Riccardo Foti, Dalila Incognito, Rosario Foti, Marco Zeppieri

DM 2024, 36(191)2333-2342; https://doi.org/10.24976/Discov.Med.202436191.215

(This article belongs to the Special Issue Immunomodulators as Adjuvant Therapies in Cancer)

Guest Editor

  • Portrait of Guest Editor Yamixa Delgado

    Yamixa Delgado

    Affiliations: San Juan Bautista School of Medicine, Caguas, Puerto Rico

    Interests: cancer therapeutics; chemoresistance; immunotherapeutics; metastasis; drug delivery systems; natural products; epilepsy therapy; epileptogenesis; inflammation; plasticity