Volume 38, Issue 208 (May 2026)

Inflammatory Low Back Pain Across Inflammatory Joint Diseases: Diagnostic Challenges and Evolving Treatment Strategies

Daniela Taneva, Mariela Geneva-Popova, Stefka Stoilova, Stanislava Popova-Belova

DM 2026, 38(208), 1327-1342; https://doi.org/10.24976/Discov.Med.202638208.105

From Sinuses to Bronchi: Molecular Endotypes and Therapeutic Convergence in CRS-Asthma Comorbidity

Saqib Muhammad, Yingqin Gao, Jing Ma

DM 2026, 38(208), 1343-1359; https://doi.org/10.24976/Discov.Med.202638208.106

Micro- and Nanoplastic Entry Into the Human Body: Ingestion, Inhalation, Dermal Absorption, and Related Toxicity—A Scoping Review

Ysatis Fagbemi, Mario Manto, Jerome R. Lechien

DM 2026, 38(208), 1360-1370; https://doi.org/10.24976/Discov.Med.202638208.107

Neuroimmune and Metabolic Dimensions of Rheumatoid Arthritis: The Gut-Brain Axis as a Therapeutic Frontier

Ozlem Ozbek, Destina Ekingen Genc, Kutlu O. Ulgen

DM 2026, 38(208), 1371-1391; https://doi.org/10.24976/Discov.Med.202638208.108

Knockdown of PRRX1 Inhibits Stemness-Associated Properties and Chemoresistance in Bladder Cancer Stem Cells

Keming Wu, Shu Li, Weiping Huang, Honghui Zhu, Xixi Huang

DM 2026, 38(208), 1392-1402; https://doi.org/10.24976/Discov.Med.202638208.109

The Immunosuppressive Checkpoint B7-H3 (CD276) Promotes Ferroptosis Resistance via AKT–SREBP2–Driven Cholesterol Metabolism in Colorectal Cancer

Cuiping Li, Qin Jin, Yuying Sun, Qing Zhang

DM 2026, 38(208), 1403-1416; https://doi.org/10.24976/Discov.Med.202638208.110

Identification of Circadian Rhythm-Related Genes in Preeclampsia by RNA-seq and Integrative Bioinformatics Analysis

Yuqing Xiang, Tianxin Zhang, Xia Ma, Jie Li, Min Jin, Xiaoxiao Jin, Feng Qi

DM 2026, 38(208), 1417-1433; https://doi.org/10.24976/Discov.Med.202638208.111

Hyperbaric Oxygen Therapy for Spinal Cord Injury: Involvement of the HIF-1alpha/HMOX1 Pathway and Ferroptosis

Xinguo Sun, Zitong Wu, Xiao Liu, Chunqiang Wang, Hongen Liu

DM 2026, 38(208), 1434-1444; https://doi.org/10.24976/Discov.Med.202638208.112

Investigating Circulating Metabolites and Proteins as Mediators of the Link Between Diabetes and Cardiovascular-Kidney-Metabolic Diseases

Bing Li, Ning Liu, Yuxing Wang

DM 2026, 38(208), 1445-1457; https://doi.org/10.24976/Discov.Med.202638208.113

Untargeted Metabolomic Profiling Reveals Bone Tissue Metabolic Alterations Associated With Acute Bone Loss Following Fracture and Unloading

Bingchao Wu, Zongrui Wang, Mingjian Bei, Xinbao Wu

DM 2026, 38(208), 1458-1477; https://doi.org/10.24976/Discov.Med.202638208.114

The Driving Effect of CSNK1E/DVL1 on the Malignant Development of Colorectal Cancer

Wei Li, Jian Chen, Jinbao Yang, Bo Zhang, Dihao Wen, Zhibin Jiang

DM 2026, 38(208), 1478-1491; https://doi.org/10.24976/Discov.Med.202638208.115

Meconium Microbiome–Metabolome Profiling at Birth Identifies Azelaic Acid as a Candidate Signal in Neonatal Hyperbilirubinemia

Zhongyuan Li, Yan Zhang, Qiuhong Wang, Lihua Peng, Xiaohong Hu, Liping Zou

DM 2026, 38(208), 1492-1506; https://doi.org/10.24976/Discov.Med.202638208.116

From Inflammatory Burden to Metabolic Imbalance: A Predictive Analysis of the Impact of Inflammation and Metabolic Indicators on Prognosis in Patients With Heart Failure—A Single-Center Retrospective Study

Yiqun Lou, Liuping Wang, Haiying Li, Xiaoqing Wang

DM 2026, 38(208), 1507-1515; https://doi.org/10.24976/Discov.Med.202638208.117

Comprehensive 16S rRNA Sequencing and Untargeted Metabolomics Analysis Reveal the Mechanism of Oral Microorganisms in Rat Dental Caries

Min Sheng

DM 2026, 38(208), 1516-1528; https://doi.org/10.24976/Discov.Med.202638208.118

Association of HbA1c and cTnI Levels With Arteriovenous Fistula Thrombosis in Hemodialysis Patients

Chunya Liu, Li Wang, Linfeng Luo, Yinbing Zhu

DM 2026, 38(208), 1529-1536; https://doi.org/10.24976/Discov.Med.202638208.119

Beyond Prolonged Fever: Synergistic Value of LDH and IL-6 for Early Stratification of Severe Mycoplasma Pneumoniae Pneumonia in Children

Ruonan Zhang, Chaoqun Zhou, Jinghua Li, Dike Huang

DM 2026, 38(208), 1537-1550; https://doi.org/10.24976/Discov.Med.202638208.120

Unveiling the Role of N-butylphthalide in Ischemic Stroke: Boosting Neural Stem Cell Proliferation via GSK-3β/NRF2 Pathway

Yuhuan Cui, Youtao Zhang, Jiahong Wu, Li Zuo, Yuanxiang Hu, Huihui Liu, Shuxian Jia, Juan Yan, Shutie Li, Zhankuang Liu

DM 2026, 38(208), 1551-1560; https://doi.org/10.24976/Discov.Med.202638208.121

Spectrum of Diseases, Risk Factors, and Prognostic Analysis of Critically Ill Obstetric Patients Transferred to the Obstetric Critical Care Unit: A Retrospective Cohort Study

Fang Xie, Xiang Wen, Shiqin Wei

DM 2026, 38(208), 1561-1569; https://doi.org/10.24976/Discov.Med.202638208.122

Regulatory Mechanism of SREBP1-Mediated Lipid Metabolic Remodeling in Osteoclast Differentiation

Xiaojun Li, Bingjian Lin, Fayi Li, Nan Zhou

DM 2026, 38(208), 1570-1582; https://doi.org/10.24976/Discov.Med.202638208.123

Esketamine Alleviates Limb Ischemia-Reperfusion-Induced Lung Injury by Inducing Macrophage Polarization

Meng Wang, Wenjuan Wang, Peng Wang, Heng Wen, Jiawei Cun, Qian Ma

DM 2026, 38(208), 1583-1596; https://doi.org/10.24976/Discov.Med.202638208.124

Unveiling the Power of Astragaloside IV: A Novel Approach to Modulating KGN Cell Proliferation and Glycolysis Through the PPARγ/GNB2/PKM2 Axis

Wenchao Zhang, Shuzhen Zhang, Bin Wang, Jun Jiang, Mingxiao Wen

DM 2026, 38(208), 1597-1609; https://doi.org/10.24976/Discov.Med.202638208.125

RNA Binding Motif Protein 15 Regulates GTPase Activating Rap/RanGAP Domain Like 3 Gene Expression as a Potential Mechanism of Temozolomide Resistance in Glioblastoma With Epidermal Growth Factor Receptor vIII Mutation

Guoxuan Luo, Sijia Cheng, Yang Zhang, Jiawen Liu, Tingting Luo, Jiayi Li, Yunzhi Ling, Jianjun Lu

DM 2026, 38(208), 1610-1626; https://doi.org/10.24976/Discov.Med.202638208.126

A Retrospective Study on the Diagnostic Efficacy of Bone Turnover Markers Combined With Inflammatory Indicators in Elderly Patients With Chronic Kidney Disease for Osteoporosis

Yangchang Chen, Suping Li, Zhenmu Jin, Xiaozuo Xu, Yingying Gong, Xuewei Cao, Qiong Wu

DM 2026, 38(208), 1627-1634; https://doi.org/10.24976/Discov.Med.202638208.127

Hypoxia Bone Marrow Mesenchymal Stem Cell-derived Exosomal AHCY Facilitates the Development of Lung Cancer via MCCC2-activated ERK Pathway

Bing Han, Feifei Ma, Junhua Hu, Zhenzhen Zheng, Chao Su, Xinnan Song

DM 2026, 38(208), 1635-1648; https://doi.org/10.24976/Discov.Med.202638208.128

Predictive Value of CRP/Albumin Ratio For Treatment Response to PTGBD in Patients With High-Risk Acute Cholecystitis

Chuncui Ye, Anqing Luo, Jun Wang

DM 2026, 38(208), 1649-1660; https://doi.org/10.24976/Discov.Med.202638208.129

Esketamine Protects Against Sepsis-Induced Intestinal Injury by Modulating Macrophage Polarization Through the TLR4/NF-κB Signaling Pathway

Liyan Miao, Li Zhang, Min Zhou, Qiuchun Chen

DM 2026, 38(208), 1661-1672; https://doi.org/10.24976/Discov.Med.202638208.130