Volume 37, Issue 193 (February 2025)

The Ubiquitin Code in Disease Pathogenesis and Progression: Composition, Characteristics and its Potential as a Therapeutic Target

Ji Su Lee, Hye Yeon Kim, Yong Tae Kwon, Chang Hoon Ji, Su Jin Lee, Su Bin Kim

DM 2025, 37(193), 203-221; https://doi.org/10.24976/Discov.Med.202537193.18

Tailoring Pharmacological Treatment in Cardiogenic Shock: A Narrative Review

Simone Pasquale Crispino, Andrea Segreti, Vincenzo Nafisio, Martina Ciancio, Ilaria Cavallari, Sara Giannone, Rosetta Melfi, Gian Paolo Ussia, Francesco Grigioni

DM 2025, 37(193), 222-243; https://doi.org/10.24976/Discov.Med.202537193.19

Channels out of Order: A Review of Central and Peripheral Nervous System Channelopathies

Lorenzo Verriello, Marco Belluzzo, Giada Pauletto, Chiara Dalla Torre, Fabiana D’Esposito, Caterina Gagliano, Mutali Musa, Chiara Bertolotti, Marco Zeppieri

DM 2025, 37(193), 244-257; https://doi.org/10.24976/Discov.Med.202537193.20

Research Progress on Alzheimer's Disease Biomarkers Based on the ATX(N) Framework

Haojun Cao, Wenxuan Zhang, Jixin Lin, Enyan Yu

DM 2025, 37(193), 258-275; https://doi.org/10.24976/Discov.Med.202537193.21

Silencing TGF-β3 Alleviates Recurrent Spontaneous Abortion Inflammation in Mice: the Importance of Treg/Th17 Cell Balance

Li Peng, Milan Yang, Xiaoyan Luo

DM 2025, 37(193), 276-285; https://doi.org/10.24976/Discov.Med.202537193.22

Urolithin B Promotes Meniscal Regeneration and Prevents the Development of Osteoarthritis in Mice

Wenjun Wang, Husheng Wang, Lin Wang, Yalin Zhang, Huihui Liu, Binbin Ci

DM 2025, 37(193), 286-298; https://doi.org/10.24976/Discov.Med.202537193.23

Prognostic Significance of a 9-Gene Signature Related to Tertiary Lymphoid Structures in Male Stomach Adenocarcinoma Patients

Zongxiang Yuan, Shihui Huang, Fang Qin, Fengyi Wang, Hailun Wei, Shengrui Luo, Yukai Zhang, Hao Liang, Junjun Jiang, Li Ye

DM 2025, 37(193), 299-314; https://doi.org/10.24976/Discov.Med.202537193.24

ELF1's Role in Colorectal Cancer: Up-Regulating DCLK1 Expression to Propel Malignant Progression and Stemness Features

Dongai Zhou, Xiaocai Tian, Hong Yang, Shengying Xiao, Yichen Lu, Furen Zeng

DM 2025, 37(193), 315-325; https://doi.org/10.24976/Discov.Med.202537193.25

GNPNAT1 Regulation: A Key Role in Radioimmune Function and NK Cell Resistance in NSCLC

Fei Xiang, Yuanfei Dai, Chunfei Yao, Ying Li, Wei Zhao, Jie Wei

DM 2025, 37(193), 326-334; https://doi.org/10.24976/Discov.Med.202537193.26

Mechanisms of Age Differences in the Effectiveness of Phototherapy of Glioblastoma

Alexander Shirokov, Nikita Navolokin, Alla Bucharskaya, Inna Blokhina, Andrey Terskov, Maria Tzoy, Alexander Dubrovsky, Ivan Fedosov, Oxana Semyachkina-Glushkovskaya

DM 2025, 37(193), 335-347; https://doi.org/10.24976/Discov.Med.202537193.27

Constructing a Multivariate Predictive Model for Postoperative 90-Day Depression Risk in Non-Small Cell Lung Cancer Based on Preoperative Peripheral Blood NLR, LMR, and PLR

Xuefeng Wu, Li Dai, Huajing Guo, Changguo Peng, Pengfei Zhang, Lizhi Mo, Xiongfei Zhang

DM 2025, 37(193), 348-359; https://doi.org/10.24976/Discov.Med.202537193.28

The Relationship between Hematocrit Levels and Major Adverse Cardiovascular Events in Patients with Acute Myocardial Infarction

Yihui Shi, Bin Xu, Jiehong Yang, Xixi Zhao, Huifen Zhou, Jianwen Yang, Zhishan Ding, Haitong Wan

DM 2025, 37(193), 360-371; https://doi.org/10.24976/Discov.Med.202537193.29

Effects of Four Main Active Flavonoids of Coreopsis tinctoria Nutt. on Oleic Acid-Induced Lipid Metabolism and Oxidative Stress in HepG2 Cells

Li-sha Zhao, Rui-feng Liu, Yu-tong Kang, Yan-ying Chen, Yu-chan Xiao, Lan-lan Zhang, Xiao-rong Cheng

DM 2025, 37(193), 372-382; https://doi.org/10.24976/Discov.Med.202537193.30

Development of a Radiomic Model to Detect the Retromolar Canal on Panoramic Radiographs

Dongjing Zhan, Fei Wang, Donglin Zeng, Lili Hao, Li Ye, Yipin Qi, Qiong Xu

DM 2025, 37(193), 383-393; https://doi.org/10.24976/Discov.Med.202537193.31

Angiotensin II and AGTR1 in ESCC Proliferation and Invasion: Insights from the JAK/STAT3 Pathway

Bo Xie, Yuanyuan Gu, Jing Li, Hu Wang, Yuanyuan Wang

DM 2025, 37(193), 394-405; https://doi.org/10.24976/Discov.Med.202537193.32

Immunity Holds the Key to Anti-Ageing Interventions

Afsar U. Ahmed

DM 2025, 37(193), 406-408; https://doi.org/10.24976/Discov.Med.202537193.33

Renin-Angiotensin System Drives Leukemia Progression by Reprogramming the Niche

Blandine Guffroy, Laurent Miguet, Bruno Lioure, Jean-Noel Freund, Manuela Tavian

DM 2025, 37(193), 409-410; https://doi.org/10.24976/Discov.Med.202537193.34