Volume 36, Issue 189 (October 2024)

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Discovery Medicine

Print ISSN: 1539-6509Online ISSN: 1944-7930

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Volume 36, Issue 189 (October 2024)

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Role of Apolipoprotein E in Alzheimer's Disease Pathogenesis, Prognosis and Treatment

Allison B. Reiss, Mary Housny, Shelly Gulkarov, Tahmina Hossain, Brandon Locke, Ankita Srivastava, Aaron Pinkhasov, Irving H. Gomolin, Thomas Wisniewski, Joshua De Leon

DM 2024, 36(189), 1917-1932; https://doi.org/10.24976/Discov.Med.202436189.179

The Pathophysiology, Diagnosis and Management of Chronic Inflammatory Skin Diseases

Liliana Z. Tong, Rini M. Desai, Rebecca Olsen, Mitchell Davis

DM 2024, 36(189), 1933-1954; https://doi.org/10.24976/Discov.Med.202436189.180

Gut-Liver Axis: Modulating the Gut Microbiota and Its Metabolic Products as a Potential Therapeutic Strategy for the Treatment of Hepatic Ischemia-Reperfusion Injury

Jiahao Wang, Yali Yun, Xunan Dong, Xulong Wang, Haizhong Ma, Qi Fang, Juan Xia, Pengxian Tao, Dongzhi Zhang

DM 2024, 36(189), 1955-1972; https://doi.org/10.24976/Discov.Med.202436189.181

Vitamin D's Role in Cardiovascular Diseases

Hamza Islam, Syed Muhammad Hassaan, Rabia Islam, Tamur Islam, Fizza Zaidi, Haris Ur Rehman, Muhammad Muheet Ul Haque, Zoha Turabee, Maria Asim, Iftikhar Ahmad, Ahmed Kunwer Naveed

DM 2024, 36(189), 1973-1986; https://doi.org/10.24976/Discov.Med.202436189.182

Therapeutic Potential of Photobiomodulation in Diabetic Complications

Lindokuhle Hadebe, Nicolette N. Houreld

DM 2024, 36(189), 1987-1997; https://doi.org/10.24976/Discov.Med.202436189.183

Focal Adhesion Kinase (FAK) and c-Src Dependent Signal Transduction in Cell Adhesion

Kazuo Katoh

DM 2024, 36(189), 1998-2012; https://doi.org/10.24976/Discov.Med.202436189.184

Establishment of a Disease Model Using Patient-Specific Induced Pluripotent Stem Cells-Derived Trabecular Meshwork Cells in a Chinese Primary Open-Angle Glaucoma Mega-Pedigree

Huifeng Rong, Ziming Luo, Mingjun Tang, Jiaqi Tang, Kaijing Li, Runcai Yang, Zhigang Fan, Nannan Sun, Jian Ge

DM 2024, 36(189), 2013-2025; https://doi.org/10.24976/Discov.Med.202436189.185

BML-111 Modulates and Alleviates p38/MAPK Signaling Pathway and Th1/Th2/Th17 Cytokine Response in Murine Psoriasis-Like Dermatitis

Yuepeng An, Qiong Zhang, Yukun Ren, Suqing Yang, Qing Zhang

DM 2024, 36(189), 2026-2036; https://doi.org/10.24976/Discov.Med.202436189.186

The Evaluation of Gastric Cancer Lymphovascular Invasion Using CT Volume Perfusion

Yueyue Li, Liebin Huang, Lin Li, Liting Chen, Ping Chen, Xiangmeng Chen

DM 2024, 36(189), 2037-2045; https://doi.org/10.24976/Discov.Med.202436189.187

SIRT2 Alleviates Inflammatory Response, Apoptosis, and ECM Degradation in Osteoarthritic Chondrocytes by Stabilizing PCK1

Fan Zhong, Shiqiang Cen, Cheng Long, Lin Teng, Gang Zhong

DM 2024, 36(189), 2046-2054; https://doi.org/10.24976/Discov.Med.202436189.188

Curcumin Alleviates Airway Inflammation in Cough-Variant Asthmatic Rats by Modulating M1/M2 Macrophage Polarization

Hui Yang, Jing Xie, Mengqing Wang, Xian Tang, Hua Wang, Kuan Rong

DM 2024, 36(189), 2055-2062; https://doi.org/10.24976/Discov.Med.202436189.189

Synergistic Inhibition of Colorectal Cancer Cells by Autocrine Motility Factor Peptide and Glycyrrhetinic Acid

Se Gie Kim, Thanh Van Duong, Semin Lee, Ki-Jun Ryu, Hyuk-Kwon Kwon, Hee Sung Park

DM 2024, 36(189), 2063-2070; https://doi.org/10.24976/Discov.Med.202436189.190

Sevoflurane Activates PI3K/AKT Signaling Pathway by Upregulating GDF11 Expression to Attenuate Ischemia/Reperfusion Injury in Cardiomyocytes

Rong-sheng Zhou, Xiao-hong Xue, Yang Bi, Ting-ting Yang, Zhan-qin Zhang, Hao-yang Zhu, Qiang Wang

DM 2024, 36(189), 2071-2078; https://doi.org/10.24976/Discov.Med.202436189.191

Upregulation of MFAP5 Enhances COL1A1 Expression, Promoting Epithelial-Mesenchymal Transition in Gastric Cancer Cells

Yue Shi, Jia E, Xue Wu, Fang Wang

DM 2024, 36(189), 2079-2087; https://doi.org/10.24976/Discov.Med.202436189.192

Propofol Ameliorates Sepsis-Induced Myocardial Dysfunction via Anti-Apoptotic, Anti-Oxidative Properties, and mTOR Signaling

Lijun Xie, Meiling Zhao, Liwu Zong, Yifeng Yue

DM 2024, 36(189), 2088-2097; https://doi.org/10.24976/Discov.Med.202436189.193

The Regulatory Effect of Remifentanil on JNK Signaling during Remission of Flap Ischemia-Reperfusion Injury

Wei Feng, Xiao Feng, Shilei Wu

DM 2024, 36(189), 2098-2110; https://doi.org/10.24976/Discov.Med.202436189.194

HERV-Derived Syncytin-1 and Syncytin-2 as Sources of Linear and Discontinuous Epitopes in Antiphospholipid Syndrome: A Pivotal Computational Study

Lorenzo Di Palma, Rossella Talotta

DM 2024, 36(189), 2111-2131; https://doi.org/10.24976/Discov.Med.202436189.195