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Molecular Pathways of Stem Cell Maintenance and Differentiation
Editor: Khan Sharun

Submission Deadline: 31 August2024 (Status: Open)

Special Issue Editor(s)

Dr. Khan Sharun      Email 1   |   Email 2   |   Website 1   |   Website 2   |   Website 3
Division of Surgery, ICAR-Indian Veterinary Research Institute, Izatnagar, Bareilly, Uttar Pradesh, India
Interests: stem cells; regenerative medicine; animal models; platelet-rich plasma; stromal vascular fraction; wound healing; bone regeneration; therapeutics

Special Issue Information

Dear Colleagues,

As one of the important players in the field of regenerative medicine, stem cells hold tremendous potential in the understanding and treatment of a wide array of diseases. Stem cells are unique for their capacity in both self-renewal and differentiation into specialized cell types, making them central players in developmental biology and regenerative therapies. Therefore, to further deepen our understanding of stem cells, we aim to bring together a series of research articles and reviews that illuminate the molecular underpinnings of stem cell biology in this special issue.

The stem cell types covered in this special issue are wide-ranging, including embryonic and induced pluripotent stem cells as well as tissue-specific stem cells. The research studies featured in this special issue will provide insights into the signaling pathways, epigenetic regulation, and genetic factors that control the balance between stem cell maintenance and differentiation. In addition, we encourage submissions on the exploration of the intricate mechanisms that dictate the fate of stem cells, particularly deciphering how these cells decide whether to remain in their undifferentiated state or to embark on the path of becoming specific tissues and organs. By unraveling these molecular pathways, we hope to advance our knowledge of stem cell biology, which forms the foundation for developing an arsenal of new therapies and disease prophylactic strategies. Discussing the implications of these molecular insights in various fields, such as regenerative medicine, cancer biology, and drug discovery, is also one of the subtopics of this special issue.

We are hopeful the collection of articles contributed to this special issue will provide a comprehensive overview of the current state of stem cell research and showcase the critical role of molecular pathways in governing stem cell behavior. Thus, this special issue will undeniably serve as a valuable resource for researchers, clinicians, and anyone interested in the dynamic world of stem cells and their potential in transforming healthcare and science.

Dr. Khan Sharun
Guest Editor


stem cells; differentiation; maintenance; molecular pathways; regenerative medicine; epigenetics; signaling pathways; pluripotency; disease modeling; cellular fate determination

Manuscript Submission Information

Manuscripts should be submitted via our online editorial system at by registering and logging in to this website. Once you are registered, click here to start your submission. Manuscripts can be submitted now or up until the deadline. All papers will go through peer-review process. Accepted papers will be published in the journal (as soon as accepted) and meanwhile listed together on the special issue website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts will be thoroughly refereed through a double-blind peer-review process. Please visit the Instruction for Authors page before submitting a manuscript. Submitted manuscripts should be well formatted in good English.

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